Сells of buccal epithelium charge state in children with lesions of the oral mucosa at the background of acute lymphoblastic leukemia in the dynamics of the treatment

Kovach, Ilona and Khotimskaya, Julia and Lavreniuk, Yana and Buniatian, Kristina (2018) Сells of buccal epithelium charge state in children with lesions of the oral mucosa at the background of acute lymphoblastic leukemia in the dynamics of the treatment. Modern Science — Moderní věda, № 4. pp. 100-106. ISSN 2336-498X

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Abstract

To study the charge state of buccal epithelial cells (BEC) in children with lesions of the mouth mucous membrane at the background of acute lymphoblastic leukemia in the dynamics of the treatment. The charge state of BEC in 126 children with lesions of the oral mucosa at the background of acute lymphoblastic leukemia (ALBL) in different periods of its course in the dynamics of treatment has been studied. All the children were divided into two groups – the basic one (n=91) and the one of comparison (n= 35). Depending on acute lymphoblastic leukemia clinical stage all the children under examination were divided into three subgroups (the acute phase, remission, relapse). At the first acute period and at the relapse of ALBL the treatment-and-prophylactic complex including kvertsetin and polyphenol containing mucosal gel applications, the treatment of oral cavity mucosa with antimycotic agents, antiseptic with a mixture of alkaloid bisulfate with sanguinarine with chelerythrine and keratoplastic agent, probi-otic preparation INSIDE were used. At the period of remission polyphenol containing gel, kera-toplastic remedy and probiotic were administered. For the individual hygiene of mouth cavity alcohol-free lysozyme dentifrice water with anti-inflammatory effect was used. The children under study had a reduced level of BEC functional activity in comparison with norm in both groups of the patients. During treatment, there was an increase in the number of BEC moving nuclei and nuclei and plasmolemma amplitudes in the main group of children.

Item Type: Article
Uncontrolled Keywords: children, oral mucosa, acute lymphoblastic leukemia, the charge state of buc-cal epithelial cell.
Subjects: Pediatric Dentistry
Divisions: Departments > Department of Pediatric Dentistry
Depositing User: Елена Шрамко
Date Deposited: 10 Sep 2018 09:53
Last Modified: 10 Sep 2018 09:53
URI: http://repo.dma.dp.ua/id/eprint/3112

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