Influence of Silicon in the Atmosphere on Osteoarthritis Clinical Course

Syniachenko, O.V. and Khaniukov, O.O. and Yehudina, Ye.D. and Socrut, N.V. (2018) Influence of Silicon in the Atmosphere on Osteoarthritis Clinical Course. Web of Scholar, V. 5 (N 6(24). pp. 11-13. ISSN 2518-167X (print), 2518-1688 (Online)

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Abstract

Osteoarthrosis (OA) is the most common diseases of the musculoskeletal system which cause an enormous medical and social harm on the patients and the society. The risk factors of the OA development are high atmospheric concentrations of silicon compounds (Si). The purpose and the objectives of the study were the assessment of the role of silicon microelementosis in OA. The study included 105 patients with OA, with an average age of 44 and 81 years old, in the proportion of men and women as 1:5, with the duration of the disease 10 years. Using the method of atomic absorption spectrometry we determined Si content in blood and in hair, evaluated the level of the pollution with Si-containing compounds. It has been found out that silicon imbalance was typical in OA which is manifested by increasing of Si content in blood. Air pollution with silicon pollutants affects negatively the incidence of OA in regions which is accompanied by Si accumulation in patients’ hair with a subsequent impact on the rate of articular syndrome progression, the development and the severity of subchondral sclerosis, ligamentosis of knee joints, reactive synovitis and cartilage bodies, and in relation to spondylopathy inhaled Si compounds have a certain protective action.

Item Type: Article
Additional Information: DOI: https://doi.org/10.31435/rsglobal_wos/12062018/5776
Uncontrolled Keywords: osteoarthritis, course, silicon, blood, hair, atmosphere, pathogenesis
Subjects: Internal Medicine
Divisions: Departments > Department of Internal Medicine 3 (formerly - hospital therapy 2)
Depositing User: Анастасия Жигар
Date Deposited: 22 Oct 2019 07:28
Last Modified: 22 Oct 2019 07:28
URI: http://repo.dma.dp.ua/id/eprint/4389

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