Vitamin D status and viral-induced wheeze in children under three years of age

Bolbot, Y.K. and Hodiatska, K.K. and Shvaratska, O.V. and Bordii, T.A. and Alifanova, S.V. (2020) Vitamin D status and viral-induced wheeze in children under three years of age. Medical Science, V. 24 (Pt.103). P. 1764-1772. ISSN 2321-7359

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The study aimed to investigate the frequency of wheezing episodes in relation to vitamin D status in young children. Also, we explored factors associated with vitamin D deficiency and recurrent viral-induced wheeze episodes. Methods and Materials: The study enrolled 60 patients with episodic wheezing, 60 patients with recurrent wheezing, and 30 healthy individuals, all aged 6 months to 3 years. Serum vitamin D concentrations were measured in all study participants using electrochemiluminescence immunoassay. Results: Vitamin D deficiency was detected in 75% of recurrent wheezers and in 6.6% of children with episodic wheeze (P <.001). We registered an inverse relationship between the number of wheezing episodes and serum vitamin D concentrations. Children without vitamin D supplementation had substantially elevated odds of being found vitamin D deficient or recurrent wheezers. Other significant factors linked to recurrent wheezing were family history of allergy, maternal anemia during pregnancy, maternal active smoking currently. Conclusion: vitamin D deficiency and failed vitamin D supplementation are associated with the increased odds of recurrent wheezing in children of the first three years of life.

Item Type: Article
Uncontrolled Keywords: Young children, vitamin D, deficiency, wheezing.
Subjects: Pediatrics
Divisions: Departments > Department of Pediatrics 3 and Neonatology (formerly - Hospital Pediatrics 2 and Neonatology)
Depositing User: Аліна Чеботарьова
Date Deposited: 20 Jun 2020 12:10
Last Modified: 20 Jun 2020 22:23

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