Characteristics of biochemical values in patients with hcv infection before conducting antiviral therapy depending on vitamin D level

Nikolaychuk, Myroslava (2020) Characteristics of biochemical values in patients with hcv infection before conducting antiviral therapy depending on vitamin D level. Modern Science — Moderní věda, № 1. pp. 111-116. ISSN 2336-498X

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Abstract

The study involved 100 patients with chronic hepatitis C (HCV) who had not received antiviral therapy before. Characterization of biochemical values before antiviral therapy was performed depending on the level of vitamin D. Patients with HCV were divided into 2 groups depending on the level of vitamin D: group 1 – HCV patients with normal levels of vitamin D, group 2 – HCV patients with decreased level (deficiency and insufficiency) of vitamin D. A liver-synthesized vitamin D metabolite was defined in the blood serum – 25-hydroxycalciferol (25(OH)D), which today is an indicator of vitamin D level adequacy in the human body. To verify the diagnosis of vitamin D deficiency, a classification (M.F. Holick, 2011), adopted by the International Institute of Medicine and the Committee of Endocrinologists, was used. The study results showed that when comparing the absolute biochemistry complex values, a statistically significant difference in the level of ALT was revealed, which was confirmed by means of frequency analysis of biochemical disorders (p = 0.02). There were no differences in medians among other values

Item Type:	Article
Uncontrolled Keywords:	chronic hepatitis C, vitamin D, vitamin D deficiency.
Subjects:	Hepatology
Divisions:	Departments > Department of Infectious Diseases
Depositing User:	Елена Шрамко
Date Deposited:	30 Dec 2021 09:06
Last Modified:	30 Dec 2021 12:23
URI:	http://repo.dma.dp.ua/id/eprint/7275

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