Could really systemic inflammatory markers be predictors of COPD Progression

Basina, B.O. and Kondrateva, G.V. (2016) Could really systemic inflammatory markers be predictors of COPD Progression. The Pharma Innovation Journal, № 5 (5). pp. 91-93. ISSN 2349-8242 (print), 2277- 7695 (online)

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Inflammatory biomarkers are considered by modern researchers as one of the best markers of effectiveness of inhaled corticosteroids (ICS) at patients with COPD, but there are a few studies about their prediction opportunity for COPD progression. The study is devoted to study of the diagnostic value of some markers of systemic inflammation (CRP, fibrinogen, MMP-2 and -9, hyaluronic acid (HA) at patients with COPD, there role as predictors of COPD progression. It was determined that determination of dynamic levels of such marker of systemic inflammation as MMP-2, CRP, HA can be used as parameters for further evaluation of the clinical stability of patients during their long-term follow-up. Significant decreasing of inflammatory markers shows the adequacy of anti-inflammatory therapy of patients with COPD regardless of changes in lung function dynamic disorders.

Item Type: Article
Uncontrolled Keywords: chronic obstructive pulmonary disease, systemic inflammation, predictors, biomarkers.
Subjects: Internal Medicine
Divisions: Departments > Department of Internal Medicine 1 (formerly - Faculty Therapy and Endocrinology)
Depositing User: Анастасия Жигар
Date Deposited: 08 Jul 2016 07:07
Last Modified: 26 Jun 2017 07:19

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