Колесник, Т.В. and Косова, А.А. (2016) Упруго-эластические свойства артериальной стенки у лиц с артериальной гипертензией пожилого и среднего возраста. Кардиология: от науки к практике, № 5-6. pp. 17-29. ISSN 2312-7015
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Abstract
Определение скорости распространения пульсовой волны и центрального аортального давления является высокоинформативным и перспективным инструментом в оценке суммарного кардиоваскулярного риска. В статье отражены результаты исследования, направленного на выявление особенностей упруго-эластических свойств артериальной стенки у пациентов разных возрастных групп, анализ взаимосвязи между показателями артериальной жесткости и суточного профиля артериального давления у больных с артериальной гипертензией пожилого и среднего возраста. Objective. To study the relationship of the elastic properties of the arterial wall and features of daily profile of blood pressure in hypertensive middle and old age patients Materials and methods. The study included 48 patients with essential hypertension II stage, which were divided into 2 groups depending on age. Group I included 23 elderly patients (12 men – 52.17 % and 11 women – 47.83 %) and 25 middle-aged patients was group II (12 men – 48.00 % and 13 women – 52.00 %). The average age in groups was 65.78 (62.16; 72.14) years in group I and 54.21 (50.64; 56.39) years in group II. For the duration of hypertension, body mass index, degree of hypertension patients in both groups did not differ significantly (p > 0.05). Assessment of elastic properties of arterial wall was performed using the method of suprasуstolic sphygmography with arteriograph “TensioClinic” (“TensioMed”, Hungary). Features of daily blood pressure profile was analyzed according to the daily monitoring of blood pressure. Results. In elderly patients with a comparable level of brachial blood pressure and duration of the disease, compared with middle-aged patients, registered significantly higher level of pulse pressure (64.00 (59.00; 73.00) mmHg in the group I compared with 55.00 (48.00; 69.00) mmHg in group II, p < 0.05) and central pulse pressure (67.00 (60.10; 81.00) mmHg in the group I compared with 54.60 (44.10; 67.00) mmHg in group II, p < 0.05). It is important to note that the level of the central systolic pressure and pulse wave velocity did not differ between groups. Significant differences are revealed in a group of elderly patients in the effect of the characteristics of ABPM on central hemodynamics – the increasing in night systolic blood pressure (r = +0.625; p < 0.05 in group I and r = +0.558; p < 0.05 in group II) and pulse pressure (r = +0.590; p < 0.05 in group I and r = +0.539; p < 0.05 in group II) in group I predominantly influence on elevation of central systolic pressure as well as the average daily level of pulse pressure. Was revealed offset systolic area index (SAI) / diastolic area index (DAI) towards by SAI (53.25 (47.90; 73.10) % in group I and 48.25 (44.80; 51.30) % in group II), which indicates a deterioration of coronary perfusion and was registered only in the group of elderly patients, at the same time duration of hypertension was associated with reducing DAI (r = –0.553; p < 0.05), patient age and duration of hypertension influenced on increasing SAI (r = +0.472; p < 0.05 and r = +0.640; p < 0.05). Such influence was not revealed in group II.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | упруго-эластические свойства артериальной стенки, скорость распространения пульсовой волны, центральное артериальное давление, артериальная жесткость, суточный мониторинг артериального давления; elastic properties of the arterial wall, pulse wave velocity, central blood pressure, arterial stiffness, ambulatory blood pressure monitoring |
| Subjects: | Internal Medicine Cardiology |
| Divisions: | Departments > Department of Internal Medicine 3 (formerly - hospital therapy 2) Departments > Department of Internal Medicine |
| Depositing User: | Елена Шрамко |
| Date Deposited: | 09 Sep 2019 14:07 |
| Last Modified: | 09 Sep 2019 14:07 |
| URI: | http://repo.dma.dp.ua/id/eprint/4290 |
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