Кобеляцкий, Ю.Ю. and Царев, А.В. and Йовенко, И.А. and Дубина, В.Н. and Яковенко, Д.П. and Селезнева, У.Р. and Халимончик, В.В. (2017) Рабдомиолиз при минно-взрывной травме: современные принципы и собственный опыт интенсивной терапии. Медицина неотложных состояний, № 2 (81). pp. 128-134. ISSN 2224-0586
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Abstract
В статье обобщен опыт диагностики, профилактики и интенсивной терапии рабдомиолиза у 298 раненых с боевой минно-взрывной травмой. Определены диагностические критерии рабдомиолиза и использованы стадии развития острого повреждения почек согласно рекомендациям KDIGO Clinical Practice Guideline for Acute Kidney Injury (2012). Представлена тактика интенсивной терапии рабдомиолиза, включая использование продленной и дискретной заместительной почечной терапии. The aim of the study was to study the clinical strategies of the prevention, diagnostics and intensive care of rhabdomyolysis on the basis of modern international recommendations and our own experience in the treatment of wounded combat mine blast injury. Materials and methods. 786 patients with combat mine blast injury were treated in the ICUs of Mechnikov Dnipropetrovsk Regional Clinical Hospital from 2014 to 2016; among them there were retrospectively examined 298 patients (male, age ranged from 19 to 42 years) with clinical and laboratory signs of acute kidney injury (AKI). All patients met the diagnostic criteria for the development of rhabdomyolysis on the basis of 5-fold raised level of creatine kinase (CK) and increased level of myoglobin; they were prospectively divided into 2 groups: group I (n = 277) consisted of the patients who performed a complex of intensive care aimed at preventing further deterioration due to myoglobinuria in AKI; group II (n = 21) involved the patients who underwent renal replacement therapy. All patients’ condition was assessed daily by a scale of development stages according to the recommendations KDIGO Clinical Practice Guideline for Acute Kidney Injury (2012). Renal replacement therapy was carried out using the following methods:...
| Item Type: | Article |
|---|---|
| Additional Information: | DOI: 10.22141/2224-0586.2.81.2017.99704 |
| Uncontrolled Keywords: | рабдомиолиз; острое повреждение почек; минно-взрывная травма; заместительная почечная терапия; миоглобинурия; интенсивная терапия. rhabdomyolysis; acute kidney injury; mine blast trauma; renal replacement therapy; myoglobinuria; intensive care. рабдоміоліз; гостре пошкодження ни- рок; мінно-вибухова травма; замісна ниркова терапія; міо глобінурія; інтенсивна терапія. |
| Subjects: | Anesthesiology and Intensive care |
| Divisions: | Faculty of Postgraduate Education > Department of Anesthesiology, Intensive Care and Emergency Medicine states FPE Departments > Department of Anaesthesiology and Intensive Care |
| Depositing User: | Елена Шрамко |
| Date Deposited: | 15 Aug 2017 12:09 |
| Last Modified: | 17 Apr 2018 12:54 |
| URI: | http://repo.dma.dp.ua/id/eprint/1854 |
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