Эффективность использования фенилпирацетама в лечении пациентов с астенией органического генеза

Юрьева, Л.Н. and Шустерман, Т.И. and Коссе, И.Д. (2018) Эффективность использования фенилпирацетама в лечении пациентов с астенией органического генеза. Архів психіатрії, Т. 24 (№ 1). pp. 64-65. ISSN 2410-7484

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Abstract

Background. In the population, the frequency of the chronic form of asthenia, or chronic fatigue syndrome, reaches 2,8 %. For all types of asthenia an essential place in the treatment is non-specifi c medication, among which the phenylpiraсetam (Entrop) occupies a special place. According to a number of studies, Entrop can reduce the severity of organic asthenia and signifi cantly improves cognitive functions. Objective. To study the eff ectiveness of the medication Entrop in the treatment of patients with asthenia of organic genesis. Materials and methods. Th e study involved 15 patients with an organic emotional-labile (asthenic) disorder (F06.6), who received the medication Entrop for 30 days in a daily dose of 200 mg. Th e analysis of the clinical picture and the psychodiagnostic examination (Global Assessment of Asthenia, Asthenic State Scale, Screening-test «Suicidal Behavior», Mini-Mental State Examination) were carried out on the 1st and 30th day of therapy with medication Entrop. Results. Weakness (80 %) and fatigue (73 %) were in the leading place among the complaints. In mental status emotional lability predominated (73 %). At the psychodiagnostic examination, reliable data on the reduction of asthenia level and improvement of cognitive functioning in the treatment with Entrop were obtained. Th e investigated product was well tolerated by patients and did not cause clinically signifi cant side eff ects. Conclusions. Th e use of the medication Entrop in the treatment of organic emotional-labile (asthenic) disorder can reliably reduce the severity of asthenia of organic genesis and all its components. Th e use of Entrop signifi cantly improves cognitive functions. Th e medication Entrop can be used in complex therapy for the treatment of asthenic syndrome in patients with asthenia of organic genesis.

Item Type: Article
Additional Information: Щорічна міжнародна конференція «Українська психіатрія в світі, що швидко змінюється», 25-27 квітня 2018 р., м. Київ : Тези доповідей
Uncontrolled Keywords: астения, органический генез, лечение, фенилпирацетам (Энтроп), эффективность; asthenia, organic genesis, treatment, phenylpiracetam (Entrop), effectiveness.
Subjects: Psychiatry
Divisions: Faculty of Postgraduate Education > Department of Psychiatry FPE (merged)
Depositing User: Елена Шрамко
Date Deposited: 01 Oct 2018 12:19
Last Modified: 01 Oct 2018 12:19
URI: http://repo.dma.dp.ua/id/eprint/3299

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