Роль урогенитальных инфекций в этиопатогенезе острых пояснично-крестцовых радикулопатий

Дзяк, Л.А. and Шульга, А.А. and Шульга, А.Н. and Чеха, Е.В. (2019) Роль урогенитальных инфекций в этиопатогенезе острых пояснично-крестцовых радикулопатий. Журнал неврології ім. Б.М. Маньковського = The Journal of Neuroscience of B.M. Mankovsk, Т. 7 (№ 1). pp. 55-63. ISSN 2524-0412 (print), 2524-0420 (online)

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В статье рассмотрены особенности формирования острых пояснично-крестцовых радикулопатий у больных с урогенитальными инфекциями. Описаны основные патоморфологические составляющие поражения позвоночно-двигательного сегмента в пояснично-крестцовом отделе позвоночника, связанные с урогенитальными инфекциями. Представлены особенности клинического течения острых пояснично-крестцовых радикулопатий, ассоциированных с урогенитальными инфекциями. The aim of the study — to evaluate the role of Chlamydia-associated, Ureaplasma-associated and Mycoplasma-associated infections in the occurrence of acute lumbosacral radiculopathy. A total of 100 patients aged from 20 to 70 years with acute lumbosacral radiculopathy caused by vertebral pathology that was verified by computer tomography were examined. Patients were divided into two groups: main group consisted of patients with lumbosacral radiculopathy that was caused by disc pathology in combination with stenosis in the spinal canal and/or lateral openings (n=45); control group consisted of patients with lumbosacral radiculopathy that was caused only by disc pathology (n=55). Patients were examined for pain syndrome, musculartonic syndrome and sensory disorders in dynamics (1-7 day, 10-14 day and 30 day). For laboratory diagnosis of urogenital infections used the ELISA method (ImmunoComb® test). Ureaplasma and Mycoplasma as monoinfection were dominating in the main group (13.3%) and Chlamydia infection — in the control group (14.5%). Most infected patients had mixed infections in both groups — 46.7% in the main group and 47.3% in control. It was revealed that the most severe pain syndrome had patients with urogenital infections according to VAS, Verbal Rating Scale, PainDETECT. By the III stage of the research the fastest regression of pain was observed in patients without urogenital infections. Muscular-tonic syndrome was more pronounced in patients with urogenital infections either and regression was more torpid. Sensory impairments were significant in patients with infections as well. It can be assumed that there is a causal relationship between the latent persistence of Ureaplasma, Mycoplasma and Chlamydia infections and their destructive role in the development of morphofunctional changes in the spine. Based on the results, patients with radiculopathy should be screened for urogenital infections even in the absence of clear clinical signs of disease.

Item Type: Article
Uncontrolled Keywords: острая пояснично-крестцовая радикулопатия, урогенитальные инфекции, Chlamydia trachomatis, Ureaplasma urealiticum, Mycoplasma genitalum, реактивный артрит; acute lumbosacral radiculopathy, urogenital infections, Chlamydia trachomatis, Ureaplasma urealiticum, Mycoplasma genitalum, reactive arthritis.
Subjects: Sexually Transmitted Infections
Neurological disease
Divisions: Faculty of Postgraduate Education > Department of Neurology and Neurosurgery FPE
Depositing User: Елена Шрамко
Date Deposited: 04 Feb 2020 09:09
Last Modified: 04 Feb 2020 13:01
URI: http://repo.dma.dp.ua/id/eprint/4880

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