Vakulenko, L.I. (2019) 24-hour blood pressure profile in children with chronic pyelonephritis and chronic kidney disease stages I–III. Нирки = Почки = Kidneys, Vol. 8 (№ 3). pp. 11-17. ISSN 2307-1257 (print), 2307-1265 (online)
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Kidneys. - 2019. Vol. 8, № 3. – P. 11-17.pdf Download (465kB) | Preview |
Abstract
Background. Blood pressure (BP) monitoring is important for the management of patients with chronic kidney disease (CKD), both for the conventional cardiovascular risk reduction and long-term preservation of kidney function. The purpose was to study the features of 24-hour blood pressure profile in children with chronic pyelonephritis (CPN) and CKD stages ²–²²². Materials and methods. A total of 94 patients aged from 6 to 17 years with chronic pyelonephritis in remission and CKD stages ²–²²² were examined. 24-hour ambulatory blood pressure monitoring (ABPM) was carried out followed by mathematical processing. Results. Thus, a comparative analysis of the systolic (SBP) and diastolic blood pressure (DBP) indicators obtained within a single BP measurement and during 24-hour ABPM showed their differences in 25.5 % of cases. According to ABPM findings, 22.3 % of CKD children demonstrated elevated BP and 34.0 % — arterial hypertension (ÀÍ). It was found that the relative number of patients with sustained and labile AH gradually increased with a decrease in renal functions (mild-to-moderate CKD progression). The analysis of night-time BP dipping degree in patients with CKD revealed a gradual decrease in the relative number of patients with optimal BP dipping for both SBP (from 61.7 % in CKD stage I to 47.1 % in CKD stage III) and DBP (53.2 and 11.8 %, respectively; ð = 0.0049). Night-peakers with night-time stable elevation of SBP (11.8 %) and DBP (29.4 %) were the patients with CKD stage III. Conclusions. The number of hypertensive patients increases among CPN children during CKD progression. AH in children with progressive nephropathy is characterized by a greater contribution from DBP and stable elevation of night-time BP.
| Item Type: | Article |
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| Additional Information: | DOI: 10.22141/2307-1257.8.3.2019.176451 |
| Uncontrolled Keywords: | blood pressure; 24-hour blood pressure profile; children; chronic pyelonephritis; chronic kidney disease; артеріальний тиск; добове моніторування артеріального тиску; діти; хронічний пієлонефрит; хронічна хвороба нирок; артериальное давление; суточное мониторирование артериального давления; дети; хронический пиелонефрит; хроническая болезнь почек. |
| Subjects: | Nephrology Pediatrics |
| Divisions: | Departments > Department of Pediatrics 2 (formerly - hospital pediatrics 1) |
| Depositing User: | Елена Шрамко |
| Date Deposited: | 06 Feb 2020 13:07 |
| Last Modified: | 06 Feb 2020 13:27 |
| URI: | http://repo.dma.dp.ua/id/eprint/4903 |
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