Hemorrhagic corpus luteum: Clinical management update

Medvediev, Mykhailo V and Malvasi, Antonio and Gustapane, Sarah and Tinelli, Andrea (2020) Hemorrhagic corpus luteum: Clinical management update. Turkish Journal of Obstetrics and Gynecology, 17 (4). pp. 300-309. ISSN 2149-9322 (print); 2149-9330 (online)

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Abstract

Hemorrhagic corpus luteum (HCL) is an ovarian cyst formed after ovulation and caused by spontaneous bleeding into a corpus luteum (CL) cyst. When HCL rupture happens, a hemoperitoneum results. Clinical symptoms are mainly due to peritoneal irritation by the blood effusion. The differential diagnosis is extensive and standard management is not defined. The authors elaborated a comparison of the differential diagnosis and therapeutic modalities from the laparoscopic approach to nonsurgical, medical options because hemorrhage from HCL is often self-limiting. The authors reviewed all data implicated with the development of HCL, trying to give homogeneity to literature data. The authors analyzed extensive literature data and subdivided the medical approach into many topics. The wait-and-see attitude avoids unnecessary laparoscopic surgery using supportive therapies (antifibrinolytic, analgesics, liquid infusion, transfusions and antibiotic prophylaxis). Surgical therapy: operative management should be laparoscopic, with surgical options such as luteumectomy, ovarian wedge-shaped excision or oophorectomy. Prevention: the possibility to preserve fertility is essential, mainly in patients with bleeding disorders or undergoing anticoagulant therapy; therefore, they need estro-progestinics or GnRH analogues to prevent ovulation and avoid further episodes of HCL. This review will aid physicians in making an early diagnosis of HCL, to avoid unnecessary surgery, and use the most effective treatment.

Item Type:	Article
Additional Information:	DOI: 10.4274/tjod.galenos.2020.40359 Medvediev MV, Malvasi A, Gustapane S, Tinelli A. Hemorrhagic corpus luteum: Clinical management update. Turk J Obstet Gynecol 2020;17:300-309. http://tjoddergisi.org/archives/archive-detail/article-preview/hemorrhagic-corpus-luteum-clinical-management-upda/42491 https://www.ncbi.nlm.nih.gov/pubmed/?term=33343977
Uncontrolled Keywords:	Corpus luteum, ovarian cyst, ectopic pregnancy, laparoscopy
Subjects:	Obstetrics Gynecology
Divisions:	Departments > Department of Obstetrics and Gynecology
Depositing User:	Елена Шрамко
Date Deposited:	26 Jan 2021 13:32
Last Modified:	26 Jan 2021 13:38
URI:	http://repo.dma.dp.ua/id/eprint/6144

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