Modern possibilities targeting the reninangiotensin-aldosterone system blockade in patients with chronic heart failure: focus on valsartan

Khaniukov, O.O. and Smolianova, O.V. (2021) Modern possibilities targeting the reninangiotensin-aldosterone system blockade in patients with chronic heart failure: focus on valsartan. In: Актуальні проблеми коморбідності в клінці внутрішньої медицини: Матеріали науково-практичної конференції з міжнародною участю (Чернівці, 15-16 квітня 2021 р.). Медуніверситет, Чернівці, 2021, pp. 146-148.

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Abstract

d. The prevalence of chronic heart failure (CHF) has reached a pandemic level, and its further growth is projected. Commonly, the patients with heart failure have a significant level of co-morbidities, and comorbidity index increases with age. In such patients, it is important to avoid polypharmacy to maintain a satisfactory adherence to the recommended treatment. Therefore, it is better to choose drugs that act simultaneously on the common links in the pathogenesis of CHF and other cardiovascular pathology. Use of sartans, which affect the main pathogenetic links of both CHF and comorbid conditions, is justified in terms of reducing the total number of drugs taken by the patient, which, consequently, decreases the economic burden on the patient and improves adherence to treatment. The latter, in turn, will help improve the quality of life, reduce the number of hospitalizations and make the prognosis better. The aim. To analyze the literature regarding valsartan to reveal its benefits compared to other drugs affecting the renin-angiotensin-aldosterone system activity in the treatment of the patients with CHF. Materials and methods. A search and analysis of available literature sources for the last 30 years in the PubMed database using a combination of keywords "chronic heart failure", "valsartan", "sartan" was conducted. According to the search results, 123 articles were selected for detailed analysis.

Item Type:	Book Section
Subjects:	Internal Medicine
Divisions:	Departments > Department of Internal Medicine 3 (formerly - hospital therapy 2)
Depositing User:	Елена Шрамко
Date Deposited:	25 Nov 2021 08:31
Last Modified:	25 Nov 2021 08:31
URI:	http://repo.dma.dp.ua/id/eprint/7167

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