The effect of Aronia melanocarpa extract on the phospholipid composition of the rat myocardium during stress

Shvets, V. and Maslak, H. and Davydov, V. and Berest, H. and Nosulenko, I. (2022) The effect of Aronia melanocarpa extract on the phospholipid composition of the rat myocardium during stress. Ceska a Slovenska Farmacie = Czech and Slovak pharmacy, 71 (3). 98–102-98–102. ISSN 1210-7816 (Print), 1805-4439 (Online)

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Abstract

The research was performed on 80 male rats of the Wistar line. Animals of two age groups were used: adults (10–12 months) and old (22–25 months). The obtained data show that the development of immobilization stress in adult and aged rats are accompanied by the formation of a characteristic complex of changes in the phospholipid composition of the myocardium. Intraperitoneal injection of the chokeberry extract (Aronia melanocarpa) at a dose of 0.2 g/kg 60 minutes before the immobilization has limited stress modulation of myocardial phospholipid composition in aged animals. Thus, the extract of Aronia melanocarpa increases the myocardial resistance to the injury effect of stress. Výzkum byl proveden na 80 samcích potkanů linie Wistar. Byla použita zvířata dvou věkových skupin: dospělí (10–12 měsíců) a staří (22–25 měsíců). Získaná data ukazují, že rozvoj imobilizačního stresu u dospělých a starých potkanů je doprovázen tvorbou charakteristického komplexu změn ve fosfolipidovém složení myokardu. Intraperitoneální injekce extraktu z temnoplodce černoplodého (Aronia melanocarpa) v dávce 0,2 g/kg 60 minut před imobilizací má omezenou modulaci stresu složení fosfolipidů myokardu u starých zvířat. Extrakt z Aronia melanocarpa tak zvyšuje odolnost myokardu vůči negativnímu účinku stresu

Item Type:	Article
Additional Information:	Shvets V, Maslak H, Davydov V, Berest H, Nosulenko I. The effect of aronia melanocarpa extract on the phospholipid composition of the rat myocardium during stress. Ceska Slov Farm [Internet]. 2022;71(3):98-102. Available from: www.scopus.com
Uncontrolled Keywords:	aging; immobilization; myocardium; Aronia melanocarpa; stárnutí; imobilizace; myokard; Aronia melanocarpa
Subjects:	Pharmacology Biological Chemistry
Divisions:	Departments > Department of Biochemistry and medical chemistry
Depositing User:	Елена Шрамко
Date Deposited:	16 Sep 2022 12:04
Last Modified:	16 Sep 2022 12:04
URI:	http://repo.dma.dp.ua/id/eprint/7842

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