Atopy as a basis for recurrent respiratory infections in children

Височина, І.Л. and Крамарчук, В.В. (2023) Atopy as a basis for recurrent respiratory infections in children. In: Global Society in Formation of New Security System and World Order: Proceedings of the 2nd International Scientific and Practical Internet Conference, July 27-28, 2023. FOP Marenichenko V.V. Dnipro, Dnipro, Ukraine. 2023, pp. 35-36. ISBN 978-617-8293-14-7

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Abstract

Recurrent respiratory infections (RRIs) are a common clinical condition in children, with about 25% of children under 1 year of age and 6% of children during the first 6 years of life having recurrent RRIs. In most cases, infections occur with mild clinical manifestations, and the frequency of episodes tends to decrease with time, with complete resolution by 12 years. RRIs significantly reduce the quality of life of children and families and lead to significant medical and social costs. Reducing risk factors (eg, passive smoking, pacifier use, attending a day hospital) is the first strategy against respiratory relapses, but this does not always work. [2] Most infectious episodes occurring in children with recurrent respiratory infections are viral in origin, so bacterial vaccines and antibiotics do not play a prophylactic role. Allergy can contribute to the recurrent course of ARI because allergic inflammation causes overexpression of adhesion molecules, which makes allergic patients more susceptible to viral infections, impairs interferon production, and promotes microbial overgrowth. Purpose: to determine whether there is a connection between atopy and recurrent acute respiratory syndrome in children 5-7 years old, to evaluate the cytological portrait of their mucous upper respiratory tract. Materials and methods. Examination of children included: general clinical examination, microscopic examination of a smear-imprint from the nasal mucosa. The main group is children aged 5-7 years with recurrent upper respiratory tract infections (n=30). The control group is children 5-7 years old who suffer from GRI episodically (n=10). Inclusion criteria: main group - 8 or more episodes of GRI per year, one or more episodes of upper respiratory tract infection per month from September to April, state of somatic well-being at the time of examination. Control group (children who do not fall under the criteria of recurrent acute coronary syndrome).

Item Type:	Book Section
Subjects:	Pediatrics
Divisions:	Faculty of Postgraduate Education > Department of Family Medicine FPE
Depositing User:	Аліна Чеботарьова
Date Deposited:	12 Sep 2023 07:29
Last Modified:	12 Sep 2023 11:54
URI:	http://repo.dma.dp.ua/id/eprint/8536

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