Gender hormones and non-specificbronchial hypersensitivity in children with bronchial asthma

Bashkirova, N.S. (2022) Gender hormones and non-specificbronchial hypersensitivity in children with bronchial asthma. In: The 14th International scientific and practical conference “Modern stages of scientificresearch development” (December 27 - 30, 2022) Prague, Czech Republic.International Science Group. Prague, Czech Republic.International Science Group, Prague, Czech Republic, pp. 239-241. ISBN 979-8-88862-818-8

Text GENDER HORMONES....pdf Download (117kB)

Abstract

Bronchial asthma continues to occupy a leading place in thestructure of chronic respiratory diseases in adults and children. Therefore,bronchial asthma remains an actual scientific problem today.One of the main links in the pathogenesis of bronchial asthma is bronchialhyperreactivity (non-specific bronchial hypersensitivity). On the other hand,among the etiological and pathogenetic factors of the development of bronchial asthma,a certain role belongs to violations of the neuroendocrine regulation of the body, whichis performed by the hypothalamic-pituitary-adrenal system. The hormonal defensemechanism of the body is triggered due to a state of stress reaction, which causesincreased activity of the pituitary gland, which in turn activates the adrenal cortex. Themain hormones of the adenohypophysis play a key role in the process of physiologicalmaturation of the body and the establishment of reproductive function. Theendocrine status of children and adolescents is characterized by the immaturity of the"hypothalamus - pituitary gland - gonads and target organs" system. In suchconditions, the negative impact of exo- and endogenous factors during the formationof the reproductive system can cause its functional immaturity. It is a well-known factthat sex hormones are included in the mechanisms of adaptation reactions.It is from the age of 12 that there is a significant restructuring of the functionalactivity of the pituitary-adrenal-gonadal status and a qualitative change in thehypothalamic-pituitary-gonadal relationship in the system of negative and positivefeedback.The purpose of the study: to study the relationship between puberty and the stateof non-specific bronchial sensitivity in children suffering from bronchial asthma.

Item Type:	Book Section
Additional Information:	DOI: 10.46299/ISG.2022.2.14
Uncontrolled Keywords:	gender hormones, non-specificbronchial hypersensitivity, children, bronchial asthma
Subjects:	Family Medicine
Divisions:	Departments > Department of Internal Medicine
Depositing User:	Аліна Чеботарьова
Date Deposited:	27 Sep 2023 09:49
Last Modified:	27 Sep 2023 09:49
URI:	http://repo.dma.dp.ua/id/eprint/8583

Actions (login required)

View Item