Predicting the occurrence of primary open-angleglaucoma depending on the genetic polymorphismendothelial no synthase (nos3) gene

Serdiuk, V.M. and Isaiev, O.A. and Ziablitsev, D. (2022) Predicting the occurrence of primary open-angleglaucoma depending on the genetic polymorphismendothelial no synthase (nos3) gene. Wiadomości Lekarskie, 75 (12). pp. 3087-3093. ISSN 0043-5147 (Print), 2719-342X (Online)

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Abstract

To develop the model for predicting primary open – angle glaucoma (POAG) depending on the presence of the genetic polymorphism in the endothelial NO-synthase (NOS3) gene. : The results of the study proved the importance of risk genotypes (TT rs1799983 and CC rs 2070744) for the development of POAG in patients from the Ukrainian population. It has been shown that the significant increase in the risk of POAG exists for carriers of the GT-CC and TT-CC haplotypes. Predicting the occurrence of primary open-angleglaucoma depending on the genetic polymorphismendothelial no synthase (nos3) gene.

Item Type:	Article
Additional Information:	DOI: 10.36740/WLek202212133
Uncontrolled Keywords:	primary open-angle glaucoma, NOS3, rs1799983 (G894T, Glu298Asp), rs2070744 (T-786C)
Subjects:	Ophthalmology
Divisions:	Departments > Department of Ophthalmology
Depositing User:	Аліна Чеботарьова
Date Deposited:	03 Oct 2023 07:40
Last Modified:	03 Oct 2023 07:41
URI:	http://repo.dma.dp.ua/id/eprint/8591

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