Limited impact of roselle flower extract on protein carbonyl levels after physical exercise in healthy men

Ayubi, N. and Rusdiawan, A. and Hartoto, S., and Wibawa, J.C. and Rizki, A.Z. and Afandi, A. and Wardani, A.P.S. and Halip, M.F. and Jr, P.B.D. (2025) Limited impact of roselle flower extract on protein carbonyl levels after physical exercise in healthy men. Медичні перспективи = Medicni perspektivi (Medical perspectives) (1). pp. 117-126. ISSN 2307-0404 (print), 2786-4804 (online)

Text 117-126.pdf Download (1MB)

Abstract

Exercise-induced oxidative stress can lead to muscle damage, with protein carbonyls serving as a key biomarker of oxidative modification in proteins. Roselle flower extract contains polyphenols with potential antioxidant properties that may reduce oxidative damage after physical exercise. This study investigated whether post-exercise supplementation of roselle flower extract reduces protein carbonyl levels. A randomized controlled trial with a parallel group pre-test/post-test design was conducted, comparing a placebo group with a treatment group receiving 500 mg of roselle flower extract. The extract did not result in a statistically significant reduction in protein carbonyl levels (p>0.05). However, a non-significant decreasing trend was observed, suggesting that future studies should explore larger sample sizes and longer intervention periods to assess potential cumulative effects. Further studies should explore the effects of higher doses of roselle flower extract (e.g., >500 mg/day) and chronic supplementation over several weeks to determine its long-term impact on markers of oxidative stress

Item Type:	Article
Additional Information:	DOI: 10.26641/2307-0404.2025.1.325371
Uncontrolled Keywords:	Key words: roselle flower extract, oxidative stress, protein carbonyl, antioxidants, exercise-induced muscle damage; екстракт квітів розелли, окиснювальний стрес, карбоніл білка, антиоксиданти, пошкодження м’язів, спричинене фізичним навантаженням
Subjects:	Clinical medicine
Divisions:	University periodicals > Medical perspectives
Depositing User:	Ирина Медведева
Date Deposited:	24 Apr 2025 09:16
Last Modified:	24 Apr 2025 09:16
URI:	http://repo.dma.dp.ua/id/eprint/9358

Actions (login required)

View Item