Mannose-containing glycotopes of leucocytes in neuro-oncologial disease

Netronina, O.V. and Maslak, G.S. and Sirko, A.G. and Romanukha, D.M. (2018) Mannose-containing glycotopes of leucocytes in neuro-oncologial disease. Ukr. Biochem. J., Vol.90 (Sp.). p. 84. ISSN 2413-5003 (Online), 2409-4943 (Print)


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There is a tendency to an increase in the incidence of tumors of the central nervous system in Ukraine. Among the primary brain tumors in adults, glioblastomas predominate. With the growth, differentiation and malignization of cells, the structure of membrane glycoproteins changes. In the oncologic process, there is a change in the expression of the number of glycoconjugates on the membranes of malignant cells. Therefore, the change in glycobiological indicators in cancers can be a priority direction of the research, namely, the development and improvement of existing methods of treatment. The aim of the work was to establish quantitative changes in the glycosylation of leukocytes and separately in their lymphocyte fraction upon neuro-oncological diseases. The subject of the study were blood leukocytes of patients with brain tumors.

Item Type: Article
Additional Information: FEBS3+ Meeting – XIth Parnas Conference – Young Scientists Forum “Biochemistry and Molecular Biology for Innovative Medicine”
Subjects: Biological Chemistry
Divisions: Faculty of Postgraduate Education > Department of Neurology and Neurosurgery FPE
Depositing User: Елена Шрамко
Date Deposited: 19 Feb 2019 10:36
Last Modified: 19 Feb 2019 11:05

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