Mannose-containing glycotopes of leukocytes in neuro-oncological disease

Netronina, O.V. and Maslak, G.S. and Sirko, A.G. and Romanukha, D.M. (2018) Mannose-containing glycotopes of leukocytes in neuro-oncological disease. Ukr. Biochem. J., Vol.90 (Sp.Is.). p. 84. ISSN 2409-4943


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There is a tendency to an increase in the incidence of tumors of the central nervous system in Ukraine. Among the primary brain tumors in adults, glioblastomas predominate. With the growth, differentiation and malignization of cells, the structure of membrane glycoproteins changes. In the oncologic process, there is a change in the expression of the number of glycoconjugates on the membranes of malignant cells. Therefore, the change in glycobiological indicators in cancers can be a priority direction of the research, namely, the development and improvement of existing methods of treatment. The aim of the work was to establish quantitative changes in the glycosylation of leukocytes and separately in their lymphocyte fraction upon neuro-oncological diseases

Item Type: Article
Additional Information: FEBS3+ Meeting – XIth Parnas Conference – Young Scientists Forum “Biochemistry and Molecular Biology for Innovative Medicine”
Subjects: Neurosurgery
Biological Chemistry
Divisions: Departments > Department of Biochemistry and medical chemistry
Faculty of Postgraduate Education > Department of Neurology and Neurosurgery FPE
Depositing User: Елена Шрамко
Date Deposited: 31 Oct 2019 15:13
Last Modified: 31 Oct 2019 15:13

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