The magnesium in the pathogenesis of bronchial asthma. A review

Vysochyna, I.L. and Berezutskyi, I.V. (2024) The magnesium in the pathogenesis of bronchial asthma. A review. Перспективи та інновації науки (Серія «Педагогіка», Серія «Психологія», Серія «Медицна"), 45 (11). pp. 1840-1851. ISSN 2786-4952

Text МАГНІЙ У ПАТОГЕНЕЗІ БРОНХІАЛЬНОЇ....pdf Download (261kB)

Abstract

Big and growing prevalence of bronchial asthma, stimulates concern for search of effective methods of treatment and prevention of the disease, which significantly worsens the quality of life of patients. The researchers pay special attention to the search for key parts in pathogenesis of bronchial asthma, effect of this pathogenesis key parts would allow to improve course of the illness significantly. In recent years, there has been an increase in research on the role of microelements in the pathogenesis of bronchial asthma. The corelation between magnesium deficiency and the development of bronchial asthma has been known to scientists for more than 30 years, but only in the last few years have new data been obtained that require analysis. The purpose of the review is to provide an update onthe current evidence for the role of blood magnesium level in the pathogenesis of bronchial asthma. To achieve the purpose, was carried out an analysis of scientific researches published in Scopus, MEDLINE, PubMed, EMBASE, Web of Science. More than 200 sources were selected and analyzed, 39 publications were directly used in the review. The analysis showed that magnesium deficiency is an important part of the pathogenesis of diseases associated with inflammation, allergies, and dysfunction of the central nervous system and autonomic nervous system. Considering that all above mentioned conditions are intrinsic of bronchial asthma, studies of the corelation between this conditions and magnesium deficiency are most perspective. Bronchial asthma is frequently associated with depressive disorder, the comorbidity of two conditions is proven. It was established that the deterioration of the course of depression is associated with exacerbation of bronchial asthma, and vice versa. It has also been established that the level of magnesium deficiency has a high correlation with the severity of bronchial asthma and depression, so it can be used as a biological marker of both diseases. Magnesium deficiency correction helps improving the condition of patients with bronchial asthma and depression, so it can be used in the combined treatment of these diseases. Correction of magnesium deficiency is impossible through diet, so it requires taking magnesium medications. Correction of hypomagnesemia appears to be a promising addition to treatment of bronchial asthma and requires further research.

Item Type:	Article
Additional Information:	DOI: 10.52058/2786-4952-2024-11(45)-1840-185
Uncontrolled Keywords:	бронхіальна астма, депресія, лікування, профілактика, мікроелементи, магній, гіпомагніємія, дієта, препарати магнію; bronchial asthma, blood trace elements, magnesium
Subjects:	Family Medicine
Divisions:	Faculty of Postgraduate Education > Department of Family Medicine FPE
Depositing User:	Аліна Чеботарьова
Date Deposited:	11 Aug 2025 11:45
Last Modified:	11 Aug 2025 11:45
URI:	http://repo.dma.dp.ua/id/eprint/9576

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