Results from the Survey of Antibiotic Resistance (SOAR) 2014–16 in Ukraine and the Slovak Republic

Torumkuney, D. and Pertseva, T. and Bratus, E. and Dziublik, A. and Yachnyk, V. and Liskova, A. and Sopko, O. and Malynovska, K. and Morrissey, I. (2018) Results from the Survey of Antibiotic Resistance (SOAR) 2014–16 in Ukraine and the Slovak Republic. Journal of Antimicrobial Chemotherapy, 5. pp. 28-35. ISSN 0305-7453 (Print), 1460-2091 (Online)

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S. pneumoniae isolates collected in Ukraine (n"100) showed susceptibility 97% fratesor amoxicillin, amoxicillin/clavulanic acid, penicillin [intravenous (iv) non-meningitis] and fluoroquinolones, between 83% and 86% for oral penicillin, macrolides and cefaclor, and 75% for trimethoprim/sulfamethoxazole. Susceptibility was substantially lower in the Slovak Republic (n"95). All isolates were susceptible to ratesthe fluoroquinolones, but susceptibility to penicillin, amoxicillin, amoxicillin/clavulanic acid, cefuroxime and trimethoprim/sulfamethoxazole varied between 61% and 64%, with only 44% of isolates susceptible to the macrolides. Susceptibility of H. influenzaewasmorehomogeneous,with susceptibilitytoamoxicillin/clavulanic acid,ceftriaxone,cefuroxime, azithromycin and the fluoroquinolones seen in .90% of isolates by CLSI criteria in both countries. Much greater variability was seen across breakpoints, especially for azithromycin, cefaclor and cefuroxime. The b-lactamase rate was 5.1% (5/98) in the Slovak Republic and 7.3% (7/96) in Ukraine, but the Slovak Republic also had a relativelyhighrateofb-lactamase-negative-ampicillin-resistant(BLNAR)isolates(7.1%;7/98).

Item Type: Article
Subjects: Microbiology, Virology and Immunology
Divisions: Departments > Department of Internal Medicine 1 (formerly - Faculty Therapy and Endocrinology)
Depositing User: Оксана Мажуга
Date Deposited: 18 Jul 2019 13:14
Last Modified: 18 Jul 2019 13:14

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