Redox Homeostasis оf еhe Cell фnd еhe Role оf the Glutathione System іn Oxidative Stress

Kryvsun, V. Ye. and Seferova, M.F. (2026) Redox Homeostasis оf еhe Cell фnd еhe Role оf the Glutathione System іn Oxidative Stress. In: Пріоритетні напрямки та вектори розвитку світової науки: матеріали X Міжнародної студентської наукової конференції, м. Кременчук, 24 квітня, 2026 рік / ГО «Молодіжна наукова ліга. ТОВ «УКРЛОГОС Груп», Вінниця, pp. 280-281. ISBN 978-617-8582-39-5

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Abstract

The paper summarizes current scientific evidence on the role of the glutathione system in maintaining cellular redox homeostasis under conditions of oxidative stress. Glutathione is shown to be a key component of the antioxidant defense system, providing detoxification of reactive oxygen species, regulation of redox-dependent signaling, maintenance of cellular metabolism, and prevention of ferroptosis. The significance of the GSH/GSSG ratio as a sensitive indicator of the cellular redox state and the role of glutathione-dependent enzymes in preserving cell viability are highlighted. The analysis of recent scientific literature confirms that the glutathione system represents a promising therapeutic target for the prevention, diagnosis, and treatment of diseases associated with impaired redox homeostasis.

Item Type:	Book Section
Uncontrolled Keywords:	redox homeostasis; oxidative stress; glutathione; GSH/GSSG ratio; antioxidant defense; glutathione peroxidase; ferroptosis; reactive oxygen species; redox signaling
Subjects:	Biological Chemistry Pathological physiology
Divisions:	Departments > Physiology
Depositing User:	Аліна Чеботарьова
Date Deposited:	27 Oct 2026 12:35
Last Modified:	27 Oct 2026 12:35
URI:	http://repo.dma.dp.ua/id/eprint/10307

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