The Effect of Graphene on Redox Homeostasis and Synaptic Transmission in Neurons

Rodynskyi, R. and Chernousova, N.M. (2026) The Effect of Graphene on Redox Homeostasis and Synaptic Transmission in Neurons. In: Theoretical and empirical scientific research: concept and trends: Collection of scientific papers «ΛΌГOΣ» with Proceedings of the X International Scientific and Practical Conference, Oxford, May 8, 2026. P.C. Publishing House & UKRLOGOS Group LLC, Oxford-Vinnytsia, p. 226. ISBN 978-617-8440-90-9

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Abstract

This review summarizes current evidence on the effects of graphene and its derivatives on redox homeostasis and synaptic transmission in neurons. The main biochemical mechanisms underlying graphene-induced modulation of neuronal function are analyzed, including changes in mitochondrial redox balance, oxidative stress, ion channel activity, neurotransmitter release, and synaptic plasticity. Particular attention is paid to the concentration-dependent effects of graphene, demonstrating that low concentrations of functionalized graphene may activate antioxidant defense pathways and promote neuroplasticity, whereas higher concentrations induce mitochondrial dysfunction, oxidative damage, and neurotoxicity. These findings highlight the dual biological activity of graphene and support its potential application in neuroscience and nanomedicine.

Item Type:	Book Section
Uncontrolled Keywords:	graphene, graphene oxide, redox homeostasis, oxidative stress, neurons, synaptic transmission, mitochondrial dysfunction, neuroplasticity, reactive oxygen species, nanomedicine
Subjects:	Biological Chemistry
Divisions:	Departments > Biochemistry and Medical Chemistry
Depositing User:	Аліна Чеботарьова
Date Deposited:	29 Oct 2026 08:40
Last Modified:	29 Oct 2026 08:40
URI:	http://repo.dma.dp.ua/id/eprint/10337

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