Respiratory Microbiota Disorders in Children with Neurological Disabilities at Repeated Respiratory Diseases

Koreniuk, O. (2021) Respiratory Microbiota Disorders in Children with Neurological Disabilities at Repeated Respiratory Diseases. ScienceRise: Medical Science (№ 1). pp. 53-56. ISSN 2519-4798 (Online), 2519-478X (Print)

Text Коренюк 53-56.pdf Download (203kB)

Abstract

The relevance of the problem of recurrent respiratory diseases in children with severe neurological pathology is due tothe high frequency, severity of clinical symptoms and the protracted nature of their exacerbations, as well as the tendency to chronicity of the pathological process.The aim of the research was to study the respiratory microbiota to optimize antibacterial therapy of recurrent respiratory diseases.Materials and methods: the 16 children with severe neurological pathology at repeated respiratory diseases were examined. We used a microbiological examination of the upper respiratory tract using a deep smear from the oropharynxto identify a possible causative agent of the disease.Research results: the pronounced imbalance of the respiratory microbiota, corresponding to II and III degrees ofdysbiotic disorders, was revealed in the examined children. The feature of the microflora of the upper respiratory tractwas the dominance of Pseudomonas aeroginosa, intestinal opportunistic microflora (Klebsiella pneumoniae, Proteusvulgaris) and their frequent combination with Streptococcus pyogenus, Staphylococcus aureus and yeast-likemushrooms of the Сandida genus. The maximum degree of respiratory microbiota disorders was noted in the group ofchildren with congenital malformations of the brain and correlated with the severity of bronchopulmonary diseases.The analysis of the pathogenic microflora sensitivity to antibiotics showed high resistance of the identified microorganisms to most medicines.Conclusions: respiratory pathology in children with neurological disabilities is characterized by a recurrent andchronic bronchitis with a tendency of a protracted course which determines the duration of antibiotic therapy. The useof a non-invasive technique for the respiratory microbiota studying makes it possible to identify suspected pathogens ofbronchopulmonary diseases and optimize their treatment.

Item Type:	Article
Additional Information:	https://doi.org/10.15587/2519-4798.2021.224333
Uncontrolled Keywords:	respiratory microbiota, repeated respiratory diseases, disabled children, neurological pathology.
Subjects:	Pediatrics
Divisions:	Departments > Department of Children's Diseases
Depositing User:	Анастасия Жигар
Date Deposited:	12 Apr 2021 08:16
Last Modified:	12 Apr 2021 08:16
URI:	http://repo.dma.dp.ua/id/eprint/6430

Actions (login required)

View Item