Current concepts of myelodysplastic syndrome: literature review

Khaniukov, O.O. and Pesotskaya, L.A. and Kravchenko, O.I. and Shchukina, O.S. (2021) Current concepts of myelodysplastic syndrome: literature review. In: World science: problems, prospects and innovations. Proceedings of the 12th International scientific and practical conference. Perfect Publishing, Toronto, Canada, pp. 44-51. ISBN 978-1-4879-3793-5

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Abstract

Myelodysplastic syndrome (MDS) is a heterogeneous group of clonal diseases of the blood system arising from mutation of the hematopoietic stem cell and characterized by cytopenia as a result of ineffective hematopoiesis, signs of dysmyelopoiesis and a high risk of transformation into acute leukemia. More than 80% of patients with MDS are over 60 years old. About 25 thousand new cases are diagnosed annually in Europe. Given the steady aging of the European population, it is believed that the number of patients with MDS will only increase in the coming decades. In addition, signs of myelodysplasia can be detected in the bone marrow or peripheral blood, not only in MDS, but also in other non-clonal diseases. The role of thyroid hormones in hematopoiesis is known, which does not exclude the development of dysmyelopoiesis in hypothyroidism.

Item Type:	Book Section
Additional Information:	Khaniukov O. O., Pesotskaya L. A., Kravchenko O. I., Shchukina O. S. Current concepts of myelodysplastic syndrome: literature review // World science: problems, prospects and innovations. Proceedings of the 12th International scientific and practical conference. Perfect Publishing. Toronto, Canada. 2021. Pp. 44-51. URL: https://sci-conf.com.ua/xii-mezhdunarodnaya-nauchno-prakticheskaya-konferentsiyaworld-science-problems-prospects-and-innovations-11-13-avgusta-2021-godatoronto-kanada-arhiv/.
Uncontrolled Keywords:	myelodysplastic syndrome, single-line dysplasia, severe hypothyroidism
Subjects:	Internal Medicine Hematology
Divisions:	Departments > Department of Internal Medicine 3 (formerly - hospital therapy 2)
Depositing User:	Елена Шрамко
Date Deposited:	27 Sep 2021 07:11
Last Modified:	27 Sep 2021 07:11
URI:	http://repo.dma.dp.ua/id/eprint/6949

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