Features of the pre-pregnancy period in women with urticaria, which often recur

Dityatkovska, E. and Nedogibchenko, N. and Vasylenko, T. and Koretskaya, E. (2021) Features of the pre-pregnancy period in women with urticaria, which often recur. Sciences of Europe, № 74 (74). pp. 8-11. ISSN 3162-2364

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Abstract

The article presents materials on the etiology, pathogenesis, clinical manifestations of chronic recurrent urticaria in women undergoing a program of pre-pregnancy training [15]. Generalized clinical observations to optimize pregnancy planning and treatment. Quality of life indicators were assessed using a questionnaire [13]. An initial examination was performed 3 months before the planned pregnancy - anamnesis taking, inspection, physical examination. Patients were examined the gastrointestinal tract: fibrogastroduodenoscopy with Helicobacterpylori. 23 patients were treated, 1 of whom did not complete the course of treatment due to spontaneous pregnancy. According to epidemiological statistical studies, there is an increase in cases of allergies. The indicators range within 30% among the country's population. Treatment during pregnancy is a difficult task. The pharmacological effects of drugs on the mother and fetus may be unpredictable. These drugs can lead to delayed adverse effects on the embryo [9.10.12] During pregnancy the function of the cellular immune system decreases, which leads to an increase in the number of T-suppressors. This effect last from 8 weeks to 32 weeks of pregnancy. From an immunological point of view, pregnancy is a condition characterized by physiological immunosuppression that provides implantation and childbearing [5.6.9]. The task of planning a pregnancy of a woman with chronic recurrent urticaria is to correct health disorders [2.4]. Patients with chronic recurrent urticaria have a reduced quality of life and efficiency. All this leaves an imprint on socioeconomic and psychological self-esteem of women [11]. Experts in many countries are studying methods to control the symptoms of the disease [17]. The combination of different antihistamines in therapy, including montelukast, omalizumab, cyclosporine, does not bring the desired effect [6]. Due to the polyetiology of chronic recurrent urticaria, it is desirable to minimize the useing of drugs that can provoke recurrence [18]. For women, in order to prevent folic acid deficiency, is recommended a balanced diet [3,5]. Appointment of folic acid at a dose of 400-800 mcg/day, to prevent malformations and complications of pregnancy in women at risk [7.8.].

Item Type:	Article
Uncontrolled Keywords:	Chronic recurrent urticaria, omalizumab, IgE, intrauterine growth retardation, miscarriage, distress syndrome.
Subjects:	Allergology
Divisions:	Departments > Department of occupational diseases, clinical immunology and clinical pharmacology
Depositing User:	Елена Шрамко
Date Deposited:	22 Nov 2021 09:02
Last Modified:	26 Nov 2021 14:55
URI:	http://repo.dma.dp.ua/id/eprint/7149

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