COPD: Alfa-1 antitrypsin (AAT) serum concentration and the airway obstruction

Gashynova, Kateryna (2021) COPD: Alfa-1 antitrypsin (AAT) serum concentration and the airway obstruction. 8th International Workshop on Lung Health : Abstracts. Virtual Edition 13–16 January 2021 / European Respiratory & Pulmonary Diseases, Vol. 7 (1 (1)). p. 5. ISSN 2058-4881

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Abstract

AAT hereditary deficiency is proved risk factor for COPD. However, only 1 % of patients (pts) with COPD have genetically determined AAT deficiency. Aim: to evaluate serum AAT in pts with stable COPD and study whether severity of airway obstruction depends on the serum AAT concentration. Study population. Stable pts with confirmed COPD (GOLD I-IV). Exclusion criteria were gastrointestinal comorbidity, malignancy, systemic connective tissue diseases and any signs of acute inflammation. Methods: AE history during past year, post-bronchodilator spirometry (by Masterlab, Viasis), serum AAT (by kinetic immune turbodimetry) were evaluated in all pts.

Item Type:	Article
Additional Information:	https://www.touchrespiratory.com/journals/european-respiratory-pulmonary-diseases/
Subjects:	Internal diseases
Divisions:	Departments > Department of occupational diseases, clinical immunology and clinical pharmacology
Depositing User:	Елена Шрамко
Date Deposited:	24 Nov 2021 09:17
Last Modified:	24 Nov 2021 09:17
URI:	http://repo.dma.dp.ua/id/eprint/7159

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