Treatment of Arthritis with Ulcerative Colitis

Sulima, Olena and Sulyma, Volodymyr (2018) Treatment of Arthritis with Ulcerative Colitis. The Eurasia Proceedings of Science, Technology, Engineering & Mathematics (EPSTEM), 2. pp. 262-264. ISSN 2602-3199

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Abstract

: Arthritis, or joint inflammation, is the most common complication of ulcerative colitis. Twenty-five percent of people with ulcerative colitis suffer from it, and it is often found in young patients. In addition to joint pain, arthritis also causes swelling and stiffness (stiffness in the joint). With ulcerative colitis, arthritis can manifest itself in two different forms: Peripheral arthritis usually affects large joints of the hands and feet, including elbows, wrists, knees and ankles. Pain can "migrate" from one joint to another and last from a few days to several weeks. The more intense the inflammatory process in the colon, the more pronounced arthritis. To date, there are no special tests to confirm ulcerative colitis-associated arthritis. This diagnosis can be made only by eliminating other causes of pain in the joints. Fortunately, such peripheral arthritis usually does not cause a significant change in the function of the joint. Spondyloarthritis (arthritis of the intervertebral joints) causes pain and stiffness in the lower part of the spine and sacroiliac joints. In young people, these symptoms may appear much earlier than intestinal manifestations. Unlike peripheral arthritis, spondyloarthritis can lead to a significant deterioration in the function of the spine, as the amount of movement in the intervertebral joints decreases. Spondylitis usually appears at the age of about 35-45 years. In most cases, the symptoms of peripheral arthritis decrease with the disappearance of inflammation in the large intestine. After a course of drugs such as prednisolone or sulfasalazine, joint pain usually disappears. The use of Infliximab (Remicade ®) for the treatment effectively reduces inflammation and swelling of the joints. Unlike peripheral arthritis, unfortunately, in spondyloarthritis there is no such clear relationship between the disappearance of signs of inflammation in the intestine and the disappearance of joint symptoms. In such patients, non-steroidal antiinflammatory drugs (NSAIDs) are used to relieve pain and swelling of the joints. However, these drugs should be used under the supervision of a doctor, as they can provoke an exacerbation, since they irritate the intestinal mucosa. To prevent a decrease in the volume of movement in the joints it is very important to engage in exercise therapy.

Item Type:	Article
Additional Information:	International Conference on Research in Education and Science (ICRES) April 28-May 1, 2018, Marmaris/Turkey
Uncontrolled Keywords:	Arthritis, Ulcerative colitis, Treatment
Subjects:	Clinical medicine
Divisions:	Departments > Department of Surgery №1
Depositing User:	Елена Шрамко
Date Deposited:	19 Dec 2022 09:49
Last Modified:	19 Dec 2022 09:50
URI:	http://repo.dma.dp.ua/id/eprint/8012

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