Features of Anesthesia of patients with special needs. Part 2

Kravets, O. and Klygunenko, O. and Yekhhalov, V. and Kovryha, O. (2024) Features of Anesthesia of patients with special needs. Part 2. Біль, знеболення та інтенсивна терапія = Pain, anaesthesia and intensive care (3). pp. 7-14. ISSN 2519-2078 (print), 2520-226X (online)

Text 310491-Текст статті-724868-1-10-20241014.pdf Download (332kB)

Abstract

Cannabis potentially interacts with drugs commonly used for anesthesia, which can be life-threatening. Dysfunctions of various organs and systems in cannabis users classify them as patients at increased perioperative risk. When planning anesthesia, acute cannabis intoxication and chronic use should be considered, as patients with acute intoxication may require lower doses of anesthetics (but emergence from anesthesia will be significantly prolonged compared to non-intoxicated states). Chronic exposure to cannabinoids outside of acute intoxication leads to downregulation of receptors, which may result in increased anesthesia tolerance when patients abstain from cannabis before anesthesia. Regional anesthesia methods are preferred in cannabis-dependent individuals. Tolerance to propofol is increased in cannabis users. Acute cannabis intoxication mostly causes additive effects with general anesthesia drugs. Chronic cannabis use mostly results in cross-tolerance to general anesthesia drugs. Anesthesiologists, surgeons, and intensive care physicians should understand the impact of cannabis on the action of general anesthesia drugs to implement safe perioperative management.

Item Type:	Article
Additional Information:	https://doi.org/10.25284/2519-2078.3(108).2024.310491
Uncontrolled Keywords:	cannabinoids, substance interactions, local anesthesia, general anesthesia, complications, prevention. канабіноїди, взаємодія речовин, локальна анестезія, загальна анестезія, ускладнення, профілактика.
Subjects:	Anesthesiology and Intensive care
Divisions:	Faculty of Postgraduate Education > Department of Anesthesiology, Intensive Care and Emergency Medicine states FPE
Depositing User:	Анастасия Жигар
Date Deposited:	18 Oct 2024 11:45
Last Modified:	18 Oct 2024 11:45
URI:	http://repo.dma.dp.ua/id/eprint/9144

Actions (login required)

View Item