Makarenko, A. and Koldunov, V. and Bibikova, V. (2015) Cognitive impairment in primary and repeated hemorrhagic stroke and their correction with verapamil. Modern Science, № 5. pp. 97-103.
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COGNITIVE IMPAIRMENT IN PRIMARY AND REPEATED HEMORRHAGIC STROKE AND THEIR CORRECTION WITH VERAPAMIL.pdf Download (265kB) |
Abstract
The article is devoted the actual problem of modern medicine – pathogenesis and treatment of hemorrhagic stroke. In order to analyze the influence of Verapamil in preventing cognitive disorders under stroke a local hemorrhagic stroke in 60 rats was simulated there. Assessment of the cognitive function was performed by the Buresh method. We found out that rats after stroke were observed to show memory disturbances. Under stroke and after Verapamil injections the rats had a gradual decrease of disorders in primary and repeated intracerebral hemorrhage. These data suggest inhibition of calcium-dependent neurodegenerative processes in the rat cortex and cognitive disorders under Verapamil injections after stroke.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | stroke, cognitive function, Verapamil |
| Subjects: | Pathological physiology Experimental medicine |
| Divisions: | Departments > Department of Pathological Physiology |
| Depositing User: | Анастасия Жигар |
| Date Deposited: | 11 Apr 2016 12:11 |
| Last Modified: | 11 Apr 2016 12:11 |
| URI: | http://repo.dma.dp.ua/id/eprint/679 |
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