Changes in the pain threshold in rats in the 1-week development of experimental blast traumatic brain injury

Kozlova, Yu.V. and Kozlov, S.V. (2022) Changes in the pain threshold in rats in the 1-week development of experimental blast traumatic brain injury. Фізіологічний журнал : Тези доповідей Всеукраїнської конференції з нейронаук 25-27 липня 2022 р., м. Київ, Т. 68 (№ 3 д). pp. 31-32. ISSN 2522-9028

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Abstract

Today, during the war in Ukraine and around the world, a large number of explosive devices are used, as a result of which both the military and the civilian population are affected. Medium and severe injuries are diagnosed by doctors quickly. But with a mild injury, the victims often do not consult a doctor in time. However, previous studies have established that even a mild blast traumatic brain injury (bTBI) leads to significant disturbances of various brain functions, in particular central sensitivity to pain, the pathogenesis of which currently requires detailed investigation. So the aim was to establish changes in the pain threshold in rats at 1-week of the course of blast-induced brain injury in the experiment. Materials and methods: The study was performed on 18 adult male Wistar rats (mass 220-270 g) in compliance with international rules of animal keeping and humane attitude.

Item Type:	Article
Uncontrolled Keywords:	pain, bTBI, halothane.
Subjects:	Pathological anatomy Pathological physiology
Divisions:	Departments > Department of Pathological Anatomy and Forensic Medicine Departments > Department of Pathological Physiology
Depositing User:	Елена Шрамко
Date Deposited:	08 Aug 2022 12:00
Last Modified:	08 Aug 2022 12:00
URI:	http://repo.dma.dp.ua/id/eprint/7737

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