Systemic inflammation in patients with chronic obstructive pulmonary disease

Sanina, Nataliia and Pertseva, Tetyana and Panina, Svitlana (2013) Systemic inflammation in patients with chronic obstructive pulmonary disease. European Respiratory Journal, Vol.42 (S. 57). P1541. ISSN 0903-1936 (Print); 1399-3003 (Online)

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Abstract

Body: COPD is considered a systemic disease with chronic inflammation, predominantly in distal respiratory tract with the development of bronchial remodeling and reduction of pulmonary function. One of lipid mediators with important role in resolution of inflammation is lipoxin A4 - an eicosanoid derived from arachidonic acid. In order to study the severity of systemic inflammation, we assessed level of lipoxin A4 in blood plasma. Were examined 64 patients with COPD stage II-III without exacerbation, mean age 54,2 ± 1,3 yrs, 91.7% male, disease duration 12,4 ± 1,0 yrs, mean FEV1 64,2 ± 4,5%, smoking index - 15,8 ± 2,7 yrs, dyspnea by mMRC 2,1 ± 0,1 pts, CAT score - 23,2 ± 0,7 pts.

Item Type:	Article
Uncontrolled Keywords:	COPD - mechanism; Biomarkers; Systemic effect.
Subjects:	Clinical medicine
Divisions:	Departments > Department of Internal Medicine 1 (formerly - Faculty Therapy and Endocrinology) Departments > Department of Internal Medicine 3 (formerly - hospital therapy 2)
Depositing User:	Елена Шрамко
Date Deposited:	30 Mar 2021 16:09
Last Modified:	30 Mar 2021 16:10
URI:	http://repo.dma.dp.ua/id/eprint/6388

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