Sklyar, T.V. and Lavrentievа, K.V. and Kurahina, N.V. and Lykholat, T.Yu. and Papiashvil, M.G. and Lykholat, O.A. and Stepanskyi, D.O. (2022) Мonitoring of enterobacteria strains with producing of β-lactamases in males with infectiousinflammatory diseases of urogenital tract. Медичні перспективи = Medicni perspektivi (Medical perspectives) (2). pp. 110-118. ISSN 2307-0404 (print), 2786-4804 (online)
![[img]](https://repo.dma.dp.ua/style/images/fileicons/text.png) |
Text
MONITORING OF ENTEROBACTERIA STRAINS.pdf Download (527kB) |
Abstract
This article presents the findings of investigation of the microflora of 257 males with infectious-inflammatory diseases of the urogenital tract using the test system “Androflor”. The role of representatives of conditionally pathogenic microflora as the main etiological agent in occurrence of infectious-inflammatory diseases of the urogenital tract in males was shown. Its composition in 39.3±3.0% of cases was represented by bacteria of family Enterobacteriaceae, in 10.9±1.9% – by Enterococcus spp., in 3.1±1.1% – by Haemophilus spp. and in 0.4±0.1% of cases – by P. aeruginosa. Out of 101 strains of enterobacteria, 27 representatives had the ability to synthesize β-lactamases 26.7±4.4% of cultures), in particular: 16 isolates of E. coli, 5 isolates of P. mirabilis and 6 isolates of K. pneumoniae. The selected strains of enterobacteria producing β-lactamases appeared to be resistant at least to 6 tested antibiotics, which allowed referring them to categories of multi-resistant. All cultures producing β-lactamases showed resistance to penicillinеs – ampicillin and amoxiclav. In this case, resistance to at least one of the antibiotics of cephalosporin group of the third generation was noted. In addition, 83.3±2.1% of the examined isolates were characterized by resistance to macrolides – erythromycin and azithromycin, as well as to co-trimoxazole and fosfomicin. The obtained data are of practical importance to develop efficient schemes of antibiotic therapy for infectious-inflammatory diseases of the urogenital tract, caused by strains of enterobacteria producing β-lactamases
| Item Type: | Article |
|---|---|
| Additional Information: | DOI: 10.26641/2307-0404.2022.2.260282 |
| Uncontrolled Keywords: | opportunistic pathogenic microflora, urogenital tract, enterobacteria, β-lactamases, antibiotics, resistance; умовно-патогенна мікрофлора, урогенітальний тракт, ентеробактерії, β-лактамази, антибіотики, резистентність; условно-патогенная микрофлора, урогенитальный тракт, энтеробактерии, β-лактамазы, антибиотики; резистентность |
| Subjects: | Microbiology, Virology and Immunology Urology |
| Divisions: | Departments > Department of Microbiology, virology, immunology and epidemiology University periodicals > Medical perspectives |
| Depositing User: | Ирина Медведева |
| Date Deposited: | 27 Feb 2023 09:04 |
| Last Modified: | 27 Feb 2023 09:04 |
| URI: | http://repo.dma.dp.ua/id/eprint/8180 |
Actions (login required)
 |
View Item |
